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Selenium Selenium is a cofactor of glutathione peroxidase, an antioxidant enzyme active inside of cells that protects our cells from damage by free radicals produced during metabolism
Consistent with negative feedback by p21 on p53 levels (Broude et al, 2007), induction of p21 FL and p21 N , but not p21 C , decreased basal p53 levels and attenuated p53 stabilization upon nutlin-3 treatment, further validating the function of these proteins (Fig 2E)
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