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In some individuals, these excipients can provoke mild hypersensitivity reactions, manifesting as localised pruritus or erythema
Supplementation of boric acid or borate can improve antioxidant defense mechanism, stimulating activities of superoxide dismutase, glucose-6-phosphate dehydrogenase, catalase, glutathione peroxidase and glutathione-S-transferase enzymes, detoxifying reactive oxygen species and reactive nitrogen, reducing oxidative stress, and lowering DNA damage and lipid peroxidation ( In addition, boron is helpful to prevent OA, possibly by enhancing absorption of calcium, phosphorus, and magnesium, and retention of magnesium and calcium ( Cadmium Bone is the main target organ of cadmium accumulation owing to chronic exposure ( Bodo et al
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