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Louis, Missouri, USA)

In addition, the pro-oxidant/antioxidant effects of polyphenols and vitamins are context-dependent and moderate doses may be cardioprotective while supraphysiologic levels negatively affect the oxidative state or disrupt ROS-mediated signalling that is important for chemotherapy-induced killing of tumour cells (218)

Cognitive and functional influences of vildagliptin, a DPP-4 inhibitor, added to ongoing metformin therapy in elderly with type 2 diabetes

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

I think it reframes ageing, chronic disease, and recovery in a way that actually honors how the human system works