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From a medical standpoint, the most meaningful changes happen over time
Because most evidence is still preclinical or anecdotal, symptom tracking is more useful than expecting a fixed timeline
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Existing GLP1R agonists come with boxed warnings of thyroid cancer and pancreatitis, based mainly on rodent studies, where the effects of GLP1R agonism have noted species differences (For example, weight loss in rodents is mainly due to increased energy expenditure, whereas in humans it occurs via less food intake [54] )
2009;21:978-e78
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