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Noteworthy findings from a mouse model of traumatic brain injury, a condition associated with increased oxidative stress in affected brain areas [153] and considered a risk factor for AD [154], underscore that melatonin treatment enhances the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) [155] 142
Gujral JS, Knight TR, Farhood A, Bajt ML, Jaeschke H
Also, MOTS-c intervention could also improve cardiac function in diabetic rats through the cysteinerich61 (CCN1)/ extracellular regulated protein kinases1/2(ERK1/2)/recombinant early growth response protein 1 (EGR1) pathway 38
453 Emerging evidence indicates that exogenous stimuli, including fungal components, may drive and perpetuate immunosenescence
[7] [8] Medical supervision is essential
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