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In an initial phase I clinical trial, melanotan 2 was shown to increase pigmentation in all subjects included in the study [4]
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As a stimulant, phentermine is a controlled substance that has a potential risk of abuse and dependence
Metformin is currently being studied for its potential role in the treatment of HFpEF, mainly because many patients with this condition also have type 2 diabetes, and metformin could be beneficial in these patients by counteracting IR and reducing the HI associated with it and, therefore, the cardiovascular damage caused by this condition (DANHEART
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