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Furthermore, 15(S)-HETE can activate PPAR/C/EBP and Akt signaling to promote preadipocyte differentiation and lipid accumulation, and it enhances adipose tissue angiogenesis by upregulating VEGF via the PI3K/Akt/mTOR pathway (59, 60)
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Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex
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