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Interestingly, as shown in our transcriptome data, in addition to the pronounced enrichment of genes associated with JA signaling in systemic leaf tissues after GSH treatment, genes responsive to other defense phytohormones such as ethylene and salicylic acid, which are responsible for plant resistance to pathogen infection, are also highly upregulated (Supplementary Data 1), implying that GSH might also act as a signaling molecule to activate the plant systemic immune response
One for all, and the most controversial, is represented by the difficult passage through the naturally built BBB with therapeutic doses of drugs targeted at specific brain areas in a selective and safe manner (Saraiva et al., 2016
5 It belongs to a different medication class called norepinephrine and dopamine reuptake inhibitors (NDRIs)
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