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Gen Comp Endocrinol (2018) 260:517
Neither graphite nor amalgam tattoos require removal, but a biopsy is recommended to exclude melanoma when a grey-to-black pigmented lesion appears in areas distant from any restored teeth or in the absence of previous injury with a graphite pencil
All findings are limited to laboratory and experimental research settings and are not indicative of clinical performance
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We recommend longitudinal serial examinations and excision of atypical lesions or areas of clinical change
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