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Sun Y, Sun M, Liu B, et al
11 Its also important to note that taking B12 in combination with vitamin B6 and folate (rather than alone) is shown to be most effective for regulating homocysteine levels for some patients and preventing the combined risk of stroke, myocardial infarction (heart attack), and damage to heart cells
Untreated B12 deficiency worsens over time and can cause permanent neurological damage
The honest caveat: most of this evidence is from cell and animal studies
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