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Stopping the medication typically leads to weight regain, confirming it remains active

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The figure below summarizes that, to date, the structures of eight different small molecule agonists have been resolved, all of which are located near the extracellular ligand-binding pocket compared to the GLP-1 peptide

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What the Research Shows Its still too early to say definitively, but recent research is encouraging

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This article examines the current evidence on investigational GLP-1 patches, including potential wearing durations, application methods, and safety considerations, whilst highlighting the licensed injectable alternatives available through the NHS

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