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And we deliberately chose exenatide and lixisenatide because they have been used very successfully in the clinic and have a long safety record. Incorporating these GLP-1 therapies into the genome of lettuce also bypasses synthesis challenges faced by oral formulations, such as the need to adjust the stomach acid pH to be less acidic to prevent degradation, he explains

His work helped bring microdosing into public discussion and inspired new research into its possible benefits

Concerns regarding muscle loss on semaglutide are valid but require nuance

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