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This study investigates whether HMGB1 is capable of attenuating the inflammation that manifests from DCM in pre-clinical models of mouse and rat combined
Firstly, we observed that metformin was able to partially alleviate OA pain in the monosodium iodoacetate (MIA)-induced mouse model as assessed by animal behavior tests
An aliquot of processed chromatin was reverse-crosslinked (see below) and amount of recovered DNA was determined
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