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The resulting acetoxyarylamines are highly unstable, spontaneously forming arylnitrenium ions that bind to DNA (Bland & Kadlubar, 1985) and ultimately lead to mutagenesis and carcinogenesis (Kerdar et al., 1993)

In more severe cases, surgery followed by months of physiotherapy may represent the most appropriate course of treatment

A real-world data analysis of tirzepatide in the FDA adverse event reporting system (FAERS) database

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