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Dysregulation and epigenetic reprogramming of NRF2 signaling axis promote acquisition of cisplatin resistance and metastasis in head and neck squamous cell carcinoma
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Gobburu JV, et al
Supporting immune function Your immune system relies on a network of cells that communicate, activate, and respond to threats
upregulation of antioxidant enzymes like catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) glutathione peroxidase (GPx), heme oxygenase, endothelial nitric oxide synthase, and other protective proteins ( In addition to the above biological functions, carnitine also plays an important role in anti-apoptosis and protection of mitochondrial biogenesis and integrity, which are beyond the scope of this study ( Application in Diseases Carnitine, a natural compound closely related to the above-mentioned functions, has recently been found to alter the underlying disease pathology with fewer side effects ( Role of Carnitine in the Pathogenesis of NAFLD and Associated Diseases Carnitine and Multiple Hit Hypothesis in the Pathogenesis of NAFLD The prevalence of NAFLD is increasing at a tremendous rate, currently affecting about 24% of the world's population
