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88 Briefly, mT/mG mice, which possess LoxP sites flanking an mT cassette (driven under the Actin promoter, resulting in red fluorescence in all tissues and cell types), were crossed with Gcg - Cre mice (Cre expression under the glucagon ( Gcg ) or preproglucagon promoter)

Side effects observed in Phase 2 studies include nausea, vomiting, diarrhoea, decreased appetite, and injection-site reactions

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