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Reported side effects are rare and typically mild: mild redness or irritation at the application site (usually resolves with continued use or concentration adjustment), occasional skin tingling at higher concentrations (typically benign), and temporary dryness during initial use

Goud, A., Zhong, J., Peters, M., Brook, R

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Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649