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A substudy of the pivotal SURMOUNT-1 trial, results of the study suggest use of tirzepatide was associated with significant reductions in systolic blood pressure in adult patients with obesity, with results pointing to mean reductions of 7.4 mmHg with tirzepatide 5 mg, 10.6 mmHg with tirzepatide 10 mg, and 8.0 mmHg with tirzepatide 15 mg
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Manfridi A, Forloni GL, Arrigoni-Martelli E, Mancia M
Peptides are short chains of amino acids that act as building blocks of proteins
This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
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