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These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue. Sodium and chloride ions screen the peptides positive charge, so the receptor sees less of it and the welt shrinks
Access this article Similar content being viewed by others Abbreviations IAN: Inferior alveolar nerve CNST/CNT: Clinical neurosensory testing BDNF: Bone-derived neurotropic factors VAS: Visual analog scale LNI: Lingual nerve injury References Book - Chapter -6, A synopsis of minor oral surgery by George Dimitroulis Santosh P (2015) Impacted mandibular third molars: review of literature and a proposal of a combined clinical and radiological classification
