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Zoloft (sertraline) is a brand-name medication that belongs to the selective serotonin reuptake inhibitor (SSRI) class of antidepressants

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Key findings: Patients lost up to 11.2% of body weight over 72 weeks, with more than half achieving 10% weight loss at the highest dose Weight loss was metabolically meaningful, with improvements in blood pressure, lipids, and reversal of prediabetes The safety profile mirrored injectable GLP-1s, with mainly mild-to-moderate gastrointestinal effects Sean Wharton et al

2023 Nov 17