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Macrophage production was initiated on day 10 by transferring the aggregated myeloid cell forming complexes onto an adherent 6-well tissue culture plate (TPP) and medium was changed to X-VIVO 15 (Lonza) containing 2 U/mL penicillinstreptomycin, 2 mM L-glutamine, 50 M -mercaptoethanol (all Gibco) supplemented with 25 ng/mL hIL-3 and 50 ng/mL human macrophage colony stimulating factor (hM-CSF, PeproTech)

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A medication capable of addressing both issues through a single weekly injection could transform treatment approaches for a substantial patient population

We still need more long-term data to understand the full impact of GLP-1s on fertility, hormone balance, and metabolic health in PCOS