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These drugs have been the subject of dozens of rigorous trials, and produced more than 10 years of real-world evidence from millions of patients who have taken them, Mark Premo-Hopkins, an attorney at Chicago firm Kirkland & Ellis representing Eli Lilly, told the court
This was demonstrated in two randomised controlled trials (RCTs) that showed a decrease in epicardial adipose tissue in patients with T2D and obesity on liraglutide and exenatide according to echocardiography and cardiac MRI
Long-term treatment with liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has no effect on beta-amyloid plaque load in two transgenic APP/PS1 mouse models of alzheimers disease
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