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In a genetic preclinical study, embryonic GIPR knockout mice fed a high-fat diet were protected from obesity, supporting the role of GIPR antagonism as a method to promote weight loss and prevent weight gain (67)

Research profiles its selectivity for NNMT over other methyltransferases and establishes structure-activity relationships

Instead, it's part of the ascorbyl glucoside blend, used to help keep it stable and in the ideal pH range prior to being added to a cosmetic formula

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