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Safety Evaluation and Provider Decision Framework Before starting any GLP-1 medication, patients with ulcerative colitis should undergo thorough evaluation including disease activity assessment, recent colonoscopy findings, current immunosuppressive therapy, and baseline gastrointestinal symptoms
About 20-30% of users report nausea in clinical trials, and it's most common during weeks 1-4 and after each dose increase
They also noted a reduction in reactivity in the brain region that drives that the feeling of reward for all groups who received exenatide
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