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In published preclinical work, KPV has been studied for inhibiting NF-B activation in intestinal epithelial cells, with one widely cited study showing PepT1-mediated transport into colonic cells as part of its anti-inflammatory mechanism in mouse colitis models (Dalmasso et al., Gastroenterology , 2008)
OGT, O-GlcNAc transferase
Glycine is the rate-limiting factor in glutathione synthesis when paired with cysteine (NAC is a cysteine precursor)
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