+ - Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide , is a potent and orally active small peptide that has been the focus of significant research due to its potential neurogenic and neuroprotective effects
Vitamin B12 is an essential water-soluble vitamin that plays a key role in metabolism, energy production, red blood cell formation, and nervous system health
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2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Tan and Song, 2023),these damages further lead to mitochondrial dysfunction, which in turn prompts more ROS production, forming a positive feedback loop (Tan and Vlajkovic, 2023)
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