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While recent incretin-based therapies have provided pharmaceutical inroads into treatment of obesity, there remains an ongoing need for additional medicines with distinct modes of action as independent or complementary therapeutics

Am Fam Physician 83 Langan RC, Goodbred AJ (2017) Vitamin B12 deficiency: recognition and management

This is a primary reason why nausea and constipation are frequently cited side effects of GLP-1 therapy

The doublespeak triggered some backlashnot only because the company is, in fact, capitalizing on the $15 billion weight-loss drug market, but because the company also didnt explicitly mention in the voiceover that it sells the compounded version of these medications (made by combining, mixing, or altering ingredients), which arent approved by the FDA

Carnitine and carnitine esters in plasma and adipose tissue of chronic uremic patients undergoing hemodialysis