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Risk mitigation
Injecting 30-60 minutes before a planned small mealrather than on an empty stomach or immediately before large mealsreduces nausea severity by gradual gastric activation
However, among other effects, it is in part able to suppress nausea, by acting directly on the Area Postrema, (the same part of the brain that we introduced which regulates vomiting in humans) [24] , which is thought to be a contributing factor as to why dual GLP1R/GIPR agonists are able to act synergistically
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