Side Effects: Like any medication, semaglutide can cause side effects, although they are generally mild and well-tolerated
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The methionine overload would tend to decrease basal hyperhomocysteinemia rather than cause a further increase in basal hyperhomocysteinemia in patients bearing remethylation defects such as folate deficiency (associated or not with the C677T mutation of the MTHFR gene) (Durand et al, 1997a
Genetic Predispositions and Treatment Selection: Where Biomarkers Guide Decisions Individual genetic variation in GLP-1 receptor (GLP1R), GIPR, and metabolic genes (FTO, MC4R) can influence both baseline metabolic function and medication response