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Schjoedt KJ, Rossing K, Juhl TR et al (2005) Beneficial impact of spironolactone in diabetic nephropathy

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Those with an additional psychiatric comorbidity other than MDD, those with any cardiac disease and any ischemic disease that may affect IMA level, those with chronic disease or neurological disease that may affect oxidative stress parameters, those with limited mental capacity and pregnant women were not included in the study because they may confound the study results

Melatonin is a hormone essential for regulating sleep-wake cycles and offering antioxidant benefits