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1.1 Overview of sepsis pathophysiology The immunological response to the entry of microorganisms into the body and the resulting infection involves the transmigration of leukocytes and the release of cytokines, prostaglandins and other inflammatory molecules (4)

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Several previous studies have used the same platform for MDD participants 20,52,64

In terms of clinical evidence, randomized clinical trials have shown that the GLP-1 receptor agonist exenatide may reduce alcohol consumption, particularly in individuals with co-occurring alcohol use disorder and obesity (Klausen et al., 2022)