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Biochim Biophys Acta Gen Subj, 2017
The patient-reported benefit is real but confounded
Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers
The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Ferreira et al., 2013
Figure 1 Figure 2 2 Apoptosis 2.1 Apoptotic signaling pathway Apoptosis, an RCD type that has been most widely investigated and precisely regulated, is featured by cell shrinking, plasma membrane blebbing, chromatin condensation, and apoptotic bodies formation (100)
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