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Many telehealth GLP-1 providers set minimum BMI requirements of 27 or 30, which excludes people who want to use semaglutide for weight management but fall below those cutoffs
The transition from tirzepatide to retatrutide is particularly interesting because tirzepatide already activates both GLP-1 and GIP receptors
doi:10.1089/jwh.2016.5795 15
In 12 weeks, study participants who lost weight with GLP-1s or gastric bypass surgeries noted they saw at least a 20% increase in facial volume, elasticity, firmness and hydration, while experiencing a major decrease in wrinkles
doi: 10.1002/jsfa.7187 101 ZhuZ.GaoD.LiC.ChenY.ZhuM.LiuX.et al
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