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The glutathione cycle: Glutathione metabolism beyond the -glutamyl cycle [PMID: 29667297] Laboratory literature summary: The glutathione cycle: Glutathione metabolism beyond the -glutamyl cycle

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The placement of waters was confined to AMY 1 R:Cagri and CTR:Cagri ( N = 1) within the deep binding pocket in order to avoid over interpretation of the cryo-EM maps

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Ces substances exercent leur action diffrents niveaux : Effets directs sur le pancras : augmentation de l'insulinoscrtion gluco-dpendante et rduction de la scrtion de glucagon (entrainant donc une diminution de la glycmie post-prandiale) Effets indpendants du pancras : diminution de la prise alimentaire et ralentissement de la vidange gastrique par une action centrale (prsence de rcepteurs au GLP-1 dans le tronc crbral et lhypothalamus) A l'tat physiologique, ces incrtines sont trs rapidement mtabolises (demi-vie de quelques minutes) par une enzyme ubiquitaire, la DPP4 pour dipeptidyl peptidase 4

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