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The graduated escalation schedule minimizes these risks
When compared to the approved TROP2-targeting ADC, sacituzumab govitecan (Trodelvy), the preliminary ORR of 80% in a heavily pre-treated mTNBC cohort appears numerically higher than the ~ 35% ORR reported in the ASCENT trial, though cross-trial comparisons require caution due to the small initial cohort size of JSKN016
This is because IVs are able to skip the digestive system and, therefore, get to your bloodstream much faster, giving you your glutathione benefits more quickly
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