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Some patients work with their doctors to increase doses in smaller increments, such as increasing by 2.5mg instead of 5mg at each step
Over time, this cycle can cause chronically high insulin and blood sugar levels, leading to weight gain, fatigue, and eventually type 2 diabetes if left untreated
Some individuals notice improvements in energy or skin clarity within a few weeks
This pathway is designed for people in immediate medical danger, for example someone whose obesity is causing severe heart failure or who cannot breathe properly because of their weight
Acta Pharmaceutica Sinica B 4, 135-140
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