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Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides
Over time, there has been more high-quality research that has shown benefits in cardiovascular (i.e
This article covers the receptor mechanisms that differentiate these compounds, the research applications where each performs best, and what preparation and dosing errors negate their benefits entirely
doi: 10.2174/1573406411666141229163355
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