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A 2024 real-world study reported moderate weight loss, improved glycemia, and acceptable tolerability in adults with hypothalamic injury, though gastrointestinal side effects and variable response were noted [155]
Inject bacteriostatic water down the vial wall, allow natural dissolution, and refrigerate immediately
32% diarrhea and 25% reported vomiting
Although both drugs were extensively studied before approval, semaglutide has only been on the market since 2017 and tirzepatide since 2022
Wegovy, for example, is the weight-loss version of Ozempic, the most famous of the GLP-1s
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