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Tranexamic acid (when included) adds a further dimension by inhibiting melanin synthesis through a mechanism that is independent of glutathione
Pathogenesis involves antibody-mediated thyroid tissue damage, progressive fibrosis, and impaired synthesis of triiodothyronine (T3) and thyroxine (T4) (Cayres et al
However, there is currently no recognized medication therapy strategy for AKI grades 12 (Zhang and Bai, 2019
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