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The beneficial effect of tirzepatide on hsCRP, a biomarker of systemic inflammation, YKL-40, a proinflammatory cytokine, and ICAM-1, a biomarker of endothelial dysfunction, was already detectable at 4 weeks, consistent with the salutary effects of GIP and GLP-1 on inflammation and atherosclerosis in experimental models [84,85,86]
doi: 10.1136/bmj.m1086 15 De FloraS.GrassiC.CaratiL
adults, 19992018
GLP-1 RAs moving beyond injections GLP-1 receptor agonists have rapidly reshaped the treatment landscape for obesity and metabolic disease, but injections remain a sticking point for some patients
Nanomaterials, particularly silver and titanium dioxide NPs, have been shown to accumulate in the liver and kidneys of fish, negatively affecting their physiologic functioning and increasing the mortality rate
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