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They are clinically approved, evidence-based treatments used worldwide for obesity and metabolic disorders

Abstract The STEP 5 trial assessed the efficacy and safety of once-weekly subcutaneous semaglutide 2.4 mg versus placebo (both plus behavioral intervention) for long-term treatment of adults with obesity, or overweight with at least one weight-related comorbidity, without diabetes

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Circulating ghrelin levels are decreased in human obesity