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Proc Natl Acad Sci USA 94:41554160 Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW (1994) Localization of neuronal and glial glutamate transporters
6.2 NADPH: driving force for glutathione redox cycling The antioxidant activity of glutathione (GSH) critically relies on its regeneration from the oxidized form, glutathione disulfide (GSSG), through a reaction catalyzed by glutathione reductase (GR) that consumes NADPH
Minor side effects, such as mild redness or tenderness at the IV site, are normal and temporary
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Monitoring Protocol Obtain baseline ALT, AST, total bilirubin, and ALP at first presentation
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