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High homocysteine levels are problematic because they have been linked to heart disease and atherosclerosis.32 In people who are deficient or have mutations in the enzymes that catalyze the production of glutathione from homocysteine, the methylation cycle will be under pressure to remove excess homocysteine
However, many clinicians and some researchers feel there is a large grey zone between 160-500 pmol/L, which in some patients could represent functional deficiency on a cellular level
Understanding these nuances separates successful protocols from wasted investments
Benzyl alcohol-containing diluents have been associated with toxicity in certain populations including neonates.
Statements Author contributions SS: Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing original draft, Writing review & editing
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