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(Archives of Pharmacal Research, 2007) showed that GHK-Cu increased proliferation of human dermal papilla cells by 70% and upregulated genes associated with hair growth, including Wnt/beta-catenin pathway components
These may include nausea, reduced appetite, vomiting, diarrhea, constipation, abdominal discomfort, or reflux
NIH/3T3 cells were stained with 0.5 M Calcein-AM and the fluorescence was detected by CLSM
Whether systemic injection delivers ascorbic acid to the dermis in concentrations that meaningfully exceed what the body achieves through normal dietary intake has not been established in controlled skin-outcome studies
Expect gradual changes and variable responses
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