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Published data suggests ipamorelin may increase IGF-1 levels by 15-30% in responder populations, while sermorelin studies report variable outcomes ranging from modest to moderate GH elevation depending on dosing, frequency, and baseline age

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However, in cells lacking IR, IGF-1 further increased BrdU incorporation, whereas the effect of insulin was diminished as expected

This ratio drops tremendously when cells are under oxidative stress.[ref] What does glutathione do