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For people who use one of the two new GLP-1s, semaglutide (Wegovy) or tirzepatide (Zepbound) to lose weight, the results can vary from person to person
Higher amounts of GLP-1 interact with brain parts, suppressing appetite and leading to weight loss
Study done from 15 November 2022 to 15 May 2024
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This analysis specifically in ARC POMC neurons revealed that leptin receptor-expressing and GLP-1R-expressing neurons are non-overlapping [153], which was confirmed in an independent study using in situ hybridization and transgenic reporter mice [154]
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