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Loading phase (deficiency): 1000 mcg IM or subQ daily or every other day for 1 to 2 weeks Maintenance: 1000 mcg monthly is a standard maintenance dose for conditions like pernicious anemia Wellness protocols: may use lower doses weekly, though this is less established clinically In ml: cyanocobalamin is typically supplied at 1000 mcg/ml, so a 1000 mcg dose equals 1 ml
B12 shots are injected intramuscularly, which means they dont have to go through the digestive system like an oral supplement
Reconstituted: Refrigerate at 28 C (35.646.4 F) immediately after mixing
What the margin difference looks like in practice: Community sources describe the room-temperature-stored punctured vial as more likely to reach the boundary of preservative efficacy within the 28-day window still technically within the documented period, but with less safety margin
Deficiency can cause megaloblastic anaemia
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