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Methods Ethics statement Data analysis utilizing the TriNetX platform received approval from the Institutional Review Board of Chi-Mei Hospital (No: 11202-002), as well as approval from the institutional review boards of all participating hospitals

The two core mechanism papers were retracted in April 2025 (PMID 22129598, retraction notice PMID 40312092

But general guidelines do exist

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity (STEP-3)