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This effect appears primarily mediated by weight loss and reduction in ectopic fat deposition in humans, though some preclinical evidence suggests potential direct effects on insulin signaling pathways
Bounous G et al
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Retrieved from Wadden, T
It also provides practical and case-driven opinions and recommendations on the optimal use of GLP-1RAs by discussing important patient factors and clinical considerations that will help to identify those who are most likely to benefit from this class of agents
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