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Individual Risk Factors: Age, Comorbidities, and Medication Interactions Age over 65, diabetes duration, baseline kidney function, gastroparesis history, and concurrent medications all modify side effect risk

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Insights into the allosteric mechanism of setmelanotide (RM-493) as a potent and first-in-class melanocortin-4 receptor (MC4R) agonist to treat rare genetic disorders of obesity through an in silico approach

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